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National Institutes of Health

NINDS Efficacy and Exploratory Clinical Trials (UG3/UH3 - Clinical Trial Required)

Key facts

Award
Not Announced
Opens
Aug 31, 2026
Closes
Mar 9, 2029
Location
United States
Category
Healthcare

Who can apply

  • Eligible applicants include
  • higher education institutions,
  • nonprofits,
  • small businesses,
  • for-profit organizations,
  • state/county/city/local governments,
  • tribal governments/organizations,
  • independent school districts,
  • public housing authorities,
  • and foreign entities (non-domestic entities and foreign components of U.S. organizations).
  • Applications involving foreign subawards/subcontracts are noncompliant and will not be considered for funding.

About this grant

This Notice of Funding Opportunity (NOFO) encourages applications for investigator-initiated clinical trials to the National Institute of Neurological Disorders and Stroke (NINDS). These trials must address questions within the mission and research interests of the NINDS and may include studies of small molecules, biologics, devices as well as surgical, behavioral, diet-based, or rehabilitation therapies. Studies addressing neurological diseases and care across the lifespan are highly encouraged. This notice invites both early- and middle-phase exploratory clinical trials as well as later phase confirmatory Phase 3 or comparative effectiveness clinical trials.

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