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National Institutes of Health

BRAIN Initiative: Integrative Team-Research BRAIN Circuits Program - iBCP (RM1 Clinical Trial Not Allowed)

Key facts

Award
Up to $8,000,000
Opens
Aug 31, 2026
Closes
Jun 23, 2028
Location
United States
Category
Healthcare

Who can apply

  • Higher education institutions
  • Small businesses
  • Nonprofit organizations
  • State, local, and tribal governments
  • Special districts
  • Housing authorities
  • Non-domestic (non-U.S.) entities are not eligible to apply
  • Foreign subawards and subcontracts are not permitted

About this grant

This Notice of Funding Opportunity (NOFO) supports transdisciplinary research teams seeking to develop mechanistic, biologically grounded explanations of how neural circuits and their cellular building blocks give rise to central nervous system (CNS) function. Teams must integrate expertise spanning molecular and cellular through systems neuroscience, with strong collaboration between experimental and computational investigators, to bridge cells, circuits, and behavior in a unified framework that yields mechanistic insight. Proposed studies are expected to leverage innovative conceptual or theoretical frameworks, predictive models, and cutting-edge approaches.

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